0000026966 00000 n 0000013285 00000 n 0000014220 00000 n Impaired renal or … Statin Dose Comparison. Get concise advice on drug therapy, plus unlimited access to CE. 0000217422 00000 n Chart: Statin Muscle Symptoms: Managing Statin Intolerance June 2020 Article: Know How Nexletol Stacks Up to Other Non-Statins April 2020 Chart: Non-Statin Lipid-Lowering Agents March 2020 Modernized Reference Drug Program HMG-CoA Reductase Inhibitors (Statins) Fully Covered (Reference Drugs) Partially Covered (Non-Reference Drugs) Statin Dose Comparison The chart below shows statin doses expected to provide similar LDL reduction. 0000029570 00000 n trailer <]/Prev 242284/XRefStm 2805>> startxref 0 %%EOF 591 0 obj <>stream 0000190763 00000 n �j� ��)�Nq������P �a \Y�߈. Hospital Pharmacist's Letter includes:. Not sold to individuals. 0000220054 00000 n 0000213153 00000 n Upgrade Your Browser Abbreviations: ... compared to 58,60 • The Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk (FOURIER) study (NCT01764633) is ongoing and is intended to provide an assessment of the cardiovascular benefit of evolocumab.61 •Very expensive. 0000194819 00000 n 0000006473 00000 n 0000196729 00000 n 0000178342 00000 n 0000191554 00000 n 0000004695 00000 n 0000191262 00000 n 0000194051 00000 n 0000035855 00000 n 0000172911 00000 n 0000180325 00000 n 0000035551 00000 n of individual statins in our PL Chart, Characteristics of the Various Statins. 0000200570 00000 n 0000006067 00000 n 0000177795 00000 n 0000199690 00000 n 0000013767 00000 n 0000213069 00000 n We recommend that you upgrade to the latest version of Internet Explorer, Firefox, Chrome or Safari to improve your security and experience using this website. 0000172798 00000 n 0000204370 00000 n 0000014623 00000 n 0000217934 00000 n 0000205660 00000 n 0000219712 00000 n See additional information. Dosage adjustment may be needed based on renal function, race, or drug interactions. 0000190084 00000 n 0000190674 00000 n Statin-induced diabetes is most prevalent in persons already at high risk for developing diabetes. Already a subscriber? 0000197458 00000 n 0000035119 00000 n 0000035496 00000 n 0000205966 00000 n Log in. 0000197067 00000 n 0000172571 00000 n 0000205361 00000 n Log in. 0000216974 00000 n Pharmacist's Letter Canada includes: 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts; Access to the entire archive; Subscription Options. Pharmacist’s Letter/Prescriber’s Letter. 0000019027 00000 n 0000212266 00000 n Pharmacist's Letter includes: 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts; Get concise advice on drug therapy, plus unlimited access to CE . Hospital Pharmacist's Letter includes: 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts; Access to the entire archive; Learn More. 0000034695 00000 n 0000203954 00000 n 0000035667 00000 n 0000003212 00000 n 0000220429 00000 n 0000184721 00000 n 0000184893 00000 n 0000221904 00000 n 50,55 One consistent finding has been that, for each new case of incident diabetes caused by statins, several CVEs can be prevented in higher-risk patients. 0000032470 00000 n Non-Statin Lipid-Lowering Agents. 0000042795 00000 n 0000204845 00000 n 0000172283 00000 n 0000038504 00000 n 0000034853 00000 n 0000177267 00000 n Already a subscriber? 0000200457 00000 n Already a subscriber? Get unlimited access through an Enterprise license . 0000212631 00000 n 38 Discontinuation of statin therapy and failure to resume statin therapy after the occurrence of adverse drug reactions are associated with increased rates of CVEs. 0000004505 00000 n 0000184278 00000 n 0000019613 00000 n 0000173048 00000 n Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High-Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) 62 61 60 80mg ($9 … 0000180659 00000 n 0000023482 00000 n Statin Dose Comparison. h�\�=HaƟ���B�)�D�±�&���t(����#�����n�[ Get concise advice on drug therapy, plus unlimited access to CE. When compared to clinical practice, the number of patients reporting statin-associated myopathy during clinical trials remains low, primarily because patients who are susceptible to, or who have an increased risk for, statin-associated adverse events are often excluded from clinical trials. 0000035194 00000 n 0000002805 00000 n 280502. 0000032027 00000 n Statin Dose Comparison. 0000034970 00000 n 0000019436 00000 n 0000004098 00000 n 0000005135 00000 n May 2012 (full update Nov 2013). 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts When choosing a statin dose, expected LDL reduction is not the only factor to consider. %PDF-1.5 %���� 0000004061 00000 n 0000020175 00000 n 0000020600 00000 n 0000194406 00000 n 50,54 This includes older patients and those with prediabetes or metabolic syndrome. 0000002376 00000 n 0000035780 00000 n 0000002993 00000 n 0000209285 00000 n Statins are generally well tolerated; however, discontinuation rates remain high. April 2018. ph-genantidepflr-03-19. 0000191860 00000 n 0000208857 00000 n 0000014858 00000 n 0000189534 00000 n 0000183882 00000 n We no longer support this version of your browser. Log in. 3 Characteristics of Various Statins. 0000042843 00000 n 0000003256 00000 n 0000231533 00000 n Cardiovascular Disease and Depression (10), Ischemic Heart Disease/Acute Coronary Syndromes (398), Anticipated Availability of First-Time Generics, Statin Muscle Symptoms: Managing Statin Intolerance, Know How Nexletol Stacks Up to Other Non-Statins, Recommend Target Statin Doses and Consider LDL After a Stroke, 2016 AHA/ACC Guideline on Management of Lower Extremity Peripheral Artery Disease, Optimizing Care of Patients with Peripheral Artery Disease, Guide for Helping Patients Afford Their Medications, Evaluate CV Risks When Considering Statins for Patients Under Age 40, Optimize Meds for Peripheral Artery Disease.

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